8–10 Oct 2025
JW Marriott Hotel Nairobi
Africa/Nairobi timezone

ACCEPTABILITY, FEASIBILITY AND FIDELITY OF PROBLEM MANAGEMENT PLUS (PM+) FOR PREGNANT AND POSTPARTUM WOMEN LIVING WITH HIV IN A RESOURCE-LIMITED SETTING

Not scheduled
20m
Room 1 (JW Marriott Hotel Nairobi)

Room 1

JW Marriott Hotel Nairobi

JW Marriott Hotel Nairobi
Oral Presentation Community Approaches: Advocacy, education and addressing cultural issues

Speakers

Dr Linet Ongeri (Kenya Medical Research Institute)Dr Maricianah Onono (Kenya Medical Research Institute) Mercelline Ogolla-Onyando (Kenya Medical Research Institute)

Description

Introduction: Pregnant and Postpartum Women living with HIV (PPWH) face elevated risks of mental health challenges, which can impede engagement in HIV care. This study assessed the acceptability, feasibility and fidelity of the WHO's Problem Management Plus (PM+) intervention adapted for PPWH, delivered in-person and via mobile phone, in a resource-limited setting.
Methods: This cross-sectional study analyzed baseline data from 120 participants in the TATUA pilot study in Kisumu, Kenya, enrolled in March -August 2024. TATUA aims to evaluate the impact of PM+ to prevent care disengagement and viral failure among PPW. PM+ is an evidence-based psychosocial intervention delivered by trained lay health workers in weekly sessions. Participants at risk for care disengagement and viral failure based on a risk calculator developed in this study were enrolled and randomized 1:1:1 to the standard of care (N=40), 5 session in-person PM+ (N=40) and 10 session mobile PM+ (N=40) arms. Acceptability was assessed through structured surveys administered at three and six months postpartum, feasibility was evaluated based on recruitment and retention rates; and fidelity was measured by intervention coverage and session completion timelines.
Results: Among the 80 participants randomized to a PM+ arm (mean age 30, Standard Deviation =7), most were married (78%), 48% had attained secondary level education, and 5% were formally employed. Acceptability was high in both in-person and mobile delivery arms, with >95% coverage and >98% reporting positive experiences at both 3 and 6 months. Feasibility was demonstrated by a 94% enrolment rate of those eligible and 95% PM+ session completion. While fidelity was high in both arms, timely completion of all sessions was more common in the in-person arm (42.1%) than mobile (13.2%). Most participants reported improved mental health (100% at 3 and 6 months) and HIV care engagement (97% at 3 months and 100% at 6 months) with minimal disruption to daily responsibilities.
Conclusion: These findings highlight the adaptability of PM+ intervention, while pointing out the importance of addressing real-world implementation considerations in future scale-up efforts. PM+ demonstrates strong feasibility and acceptability in supporting mental health and HIV care engagement among PPWH. While the potential for scalability through mobile delivery offers a promising avenue for broader implementation and increased reach in diverse settings, there is need for greater flexibility for timely completion of the sessions.

Key words: Problem management plus, acceptability, fidelity, feasibility
References
1. Chibanda D, Shetty AK, Tshimanga M, Woelk G, Stranix-Chibanda L, Rusakaniko S. Group problem-solving therapy for postnatal depression among HIV-positive and HIV-negative mothers in Zimbabwe. J Int Assoc Provid AIDS Care. 2014;13(4):335-341.

Primary author

Mercelline Ogolla-Onyando (Kenya Medical Research Institute)

Co-authors

Prof. Anna Helova (University of Alabama) Prof. Janet Turan (University of Alabama) Dr Karen Hampanda (University of Colorado, Denver) Mr Kevin Owuor (University of Alabama) Dr Laura Beres (Johns Hopkins Bloomberg School of Public Health) Dr Linet Ongeri (Kenya Medical Research Institute) Dr Lisa Abuogi (University of Colorado, Denver) Dr Maricianah Onono (Kenya Medical Research Institute) Ms Rabbia Imran (University of Colorado, Denver)

Presentation materials